[Ca2+] |
Ca2+ concentration |
[H+] |
H+ concentration |
[Mg2+] |
Mg2+ concentration |
[Mg2+]cyto
|
cytosolic free Mg2+ concentration |
[Mg2+]ex
|
extracellular free Mg2+ concentration |
[Mg2+]mito
|
free [Mg2+] in the mitochondrial matrix |
[Mg2+]nuc
|
nuclear free [Mg2+] |
ACDP2 |
cyclin M2 |
AD |
Alzheimer’s disease |
APP |
Aβ precursor protein |
APPβ |
β-amyloid precursor protein β |
ATP |
adenosine 5’-triphosphate |
Aβ |
amyloid β |
BBB |
blood–brain barrier |
CNNM2 |
cyclin M2 |
CNS |
central nervous system |
CREB |
cAMP response element binding |
CSF |
cerebrospinal fluid |
CTFα |
C terminal fragment α |
CTFβ |
C terminal fragment β |
ECF |
extracellular cellular fluid |
ERK |
extracellular signal-regulated kinase |
GABA |
gamma-aminobutyric acid |
GSK-3β |
glycogen synthase kinase-3β |
IP3R |
inositol-1,4,5-trisphosphate receptor |
JNK |
c-Jun N-terminal kinase |
LTP |
long-term potentiation |
Mg |
magnesium |
Mg2+
|
magnesium ion |
MgT |
magnesium-L-threonate |
mitoKATP
|
mitochondrial ATP-sensitive potassium channel |
MPP+
|
N-methyl-4-phenylpyridinium iodide |
MPTP |
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
Mrs2 |
mitochondrial RNA splicing 2 |
mtDNA |
mitochondrial DNA |
mTOR |
mammalian target of rapamycin |
NF-κB |
nuclear factor-kappa B |
NMDA |
N-methyl-D-aspartate |
NSCs |
neural stem cells |
OGDH |
2-oxoglutarate dehydrogenase |
OXPHOS |
oxidative phosphorylation |
PC12 cell |
pheochromocytoma cell |
PD |
Parkinson’s disease |
PI3K |
phosphatidylinositol-3 kinase |
PKC |
protein kinase C |
PTP |
permeability transition pore |
ROS |
reactive oxygen species |
RyR |
ryanodine receptor |
sAPPα |
soluble APPα |
TCA |
tricarboxylic acid |
TRPM6 |
transient receptor potential melastatin 6 |
TRPM7 |
transient receptor potential melastatin 7 |
ΔG |
Gibbs free energy change |
ΔΨm
|
mitochondrial membrane potential |