Kaplan–Meier estimates for clinical outcome in patients stratified by ARV7 detection. (a) PSA-progression-free survival (PSA-PFS) according to ARV7 detection. Blue and red lines indicate 28 ARV7-negative (ARV7−ve) and seven ARV7-positive (ARV7+ve) patients, respectively. HR values, 95% confidence interval (CI), number of patients, and statistical significance are reported in the inset. (b) Radiologic progression-free survival (rPFS) according to AR status. Blue and red lines indicate 28 ARV7-negative (ARV7−ve) and seven ARV7-positive (ARV7+ve) patients, respectively. HR values, 95% confidence interval (CI), number of patients, and statistical significance are reported in the inset. (c) Overall survival (OS) according to ARV7 status. Blue and red lines indicate 28 ARV7-negative (ARV7−ve) and nine ARV7-positive (AR+ve) patients, respectively. HR values, 95% confidence interval (CI), number of patients, and statistical significance are reported in the inset.