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. 2019 Jul 23;20(14):3600. doi: 10.3390/ijms20143600

Figure 4.

Figure 4

AplhaScreen A2AR/D2R heteromer assessment in a PD animal model and PD post-mortem brains. (A) AlphaScreen signal obtained in human caudate from healthy control (HC) and PD subjects. (B) AlphaScreen signal obtained in striatal membranes from vehicle (Veh) and 6-OHDA-lesioned rats (see Methods). Results are presented as mean ± SEM of three independent experiments performed in triplicate. The number of samples was n = 6 for each condition. The dotted line indicates the 100 % of the signal, assigned to that obtained in HC or Veh conditions, respectively. ** p < 0.01; *** p < 0.001, Student’s t-test.