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. 2019 Jul 4;11(7):938. doi: 10.3390/cancers11070938

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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miR526b and miR655 expression is positively correlated with lymphangiogenesis markers in human breast tumours. (A) qRT-PCR analysis of VEGFD mRNA expression in control (adjacent non-tumour) and tumoural tissues. Data are represented as a mean ± SD. (*) indicates significant differences (p < 0.05). (B,C) miR526b and miR655 expression is positively correlated with the VEGFD in primary breast cancer samples; Pearson’s coefficient indicates a very strong positive correlation. (D,E) miR526b and miR655 expression level is positively correlated with another lymphangiogenesis marker VEGFC in primary breast cancer samples. Pearson’s coefficient suggests a positive correlation between the two variables. (F,G) Finally, LYVE1 mRNA expression is positively correlated with miR526b and miR655 expression in tumour samples. Pearson’s coefficient suggests a moderate correlation between the two variables.