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. 2019 Jul 3;11(7):933. doi: 10.3390/cancers11070933

Figure 1.

Figure 1

Schematic drawing of the CellCollector CANCER01 (DC01) and the application procedure. (a) Working principles of DC01 viewed from its cross section. A medical wire coated with hydrogel is functionalized with antibodies against epithelial cell adhesion molecule (EpCAM). Cancer cells expressing EpCAM antigen are targeted and captured onto the functional part. (b) Demonstration of application procedure of DC01 in vivo. The DC01 is applied into the cubital vein of the patient via a 20-gauge intravenous cannula fixed with a yellow IN-Stopper. The functional part is exposed to the blood flow for 30 min allowing the efficient detection of potential circulating tumor cells (CTCs).