Skip to main content
. 2019 Jul 22;20(14):3572. doi: 10.3390/ijms20143572

Figure 9.

Figure 9

The binding modes of nine compounds in their respective binding sites. (A,B) show the binding modes of five compounds with HIV-1 IN (PDB: 4NYF) and HCV NS5B (PDB: 1GX6), respectively, including CHEMBL16326 (red), CHEMBL18927 (pink), CHEMBL449221 (purple), CHEMBL502238 (orange) and CHEMBL19332 (gray). (C,D) show the binding modes of CHEMBL210593 with HIV-1 RT (PDB: 1TL3) and HCV NS5B (PDB: 1OS5). (E,F) show the binding modes of CHEMBL37541 with HIV-1 PR (PDB: 4MC1) and HCV NS5B (PDB: 1OS5). (G,H) show the binding modes of two compounds (CHEMBL3612421 and CHEMBL1668670) with HCV NS5B (PDB 1OS5). (The cocrystallized molecules are shown as lines, whereas the molecules modeled into the receptors are shown as sticks).