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. 2019 Jul 22;20(14):3572. doi: 10.3390/ijms20143572

Table 5.

Predicted and experimental activity of the nine selected compounds against HIV-1 protease (PR), reverse transcriptase (RT), integrase (IN) and HCV NS5B.

CHEMBL ID PR/Pred 1 PR/Exp 2 IN/Pred 3 IN/Exp 4 RT/Pred 5 RT/Exp 6 NS5B/Pred 7 NS5B/Exp 8
CHEMBL16326 false — 9 true active false — true active
CHEMBL18927 false — true active false — true active
CHEMBL449221 false — true active false — true active
CHEMBL502238 false — true active false — true active
CHEMBL19332 false — true active false active true active
CHEMBL210593 false — false — true active true active
CHEMBL37541 true active false — false — true active
CHEMBL3612421 true active false — false — true —
CHEMBL1668670 false — true active true active true —

1 “PR/Pred” shows the predicted result of a compound against PR. 2 “PR/Exp” shows the experimental result of a compound against PR.3 “IN/Pred” shows the predicted result of a compound against IN. 4 “IN/Exp” shows the experimental result of a compound against IN. 5 “RT/Pred” shows the predicted result of a compound against RT. 6 “RT/Exp” shows the experimental result of a compound against RT. 7 “NS5B/Pred” shows the predicted result of a compound against NS5B. 8 “NS5B/Exp” shows the experimental result of a compound against NS5B. 9 “—” indicates that the predicted result has not been verified by experiments.