Table 1.
Multivariate analysis to reveal population-specific differences between cohorts. AA = African American; AR = androgen receptor. Bold refers to significant p-values.
| Multivariate Cox Regression Analysis of Common Clinicopathological Variables and AR | |||||
|---|---|---|---|---|---|
| Variables | US and Nigeria Study Cohorts | Norway, Ireland and India Study Cohorts | |||
| Hazard Ratio (95% CI) | p-value | Hazard Ratio (95% CI) | p-value | ||
| Overall Survival | |||||
| Age | <50 vs. ≥50 | 1.00 (0.99–1.01) | 0.3934 | 1.03 (1.01–1.05) | <0.001 |
| Grade | 2 | 0.77 (0.86–8.84) | 0.085 | 0.25 (0.05–1.17) | 0.0801 |
| Grade | 3 | 3.63 (1.15–11.44) | 0.0275 | 0.37 (0.09–1.56) | 0.1777 |
| Adjuvant Chemotherapy | treated vs. non-treated | 0.72 (0.39–1.32) | 0.2877 | 0.91 (0.56–1.47) | 0.7026 |
| Population | AA | 1.82 (1.30–2.53) | 0.0004 | - | - |
| Population | African | 11.22 (8.11–15.51) | <0.0001 | - | - |
| Population | Indian | - | - | 0.49 (0.27–0.89) | 0.0201 |
| Population | Irish | - | - | 0.79 (0.48–1.28) | 0.3462 |
| AR | AR-positive vs. AR-negative | 1.70 (1.10–2.61) | 0.0157 | 0.58 (0.37–0.90) | 0.0154 |