Table 2.
Genotypic frequency of H19 SNP in HCC and normal controls.
| Variable | Controls (N = 1190) (%) | Patients (N = 359) (%) | OR (95% CI) | AOR (95% CI) a |
|---|---|---|---|---|
| rs217727 | ||||
| CC | 495 (41.6%) | 154 (42.9%) | 1.000 (reference) | 1.000 (reference) |
| CT | 539 (45.3%) | 170 (47.3%) | 1.014 (0.790–1.302) | 1.044 (0.802–1.358) |
| TT | 156 (13.1%) | 35 (9.8%) | 0.721 (0.479–1.085) | 0.727 (0.474–1.116) |
| rs2107425 | ||||
| CC | 422 (35.5%) | 134 (37.3%) | 1.000 (reference) | 1.000 (reference) |
| CT | 560 (47.0%) | 185 (51.5%) | 1.040 (0.806–1.344) | 1.041 (0.795–1.362) |
| TT | 208 (17.5%) | 40 (11.2%) | 0.606 (0.410–0.895) b | 0.616 (0.409–0.926) e |
| rs2839698 | ||||
| CC | 532 (44.7%) | 140 (39.0%) | 1.000 (reference) | 1.000 (reference) |
| CT | 524 (44.0%) | 178 (49.6%) | 1.291 (1.003–1.661) c | 1.353 (1.038–1.765) f |
| TT | 134 (11.3%) | 41 (11.4%) | 1.163 (0.782–1.728) | 1.165 (0.769–1.763) |
| rs3024270 | ||||
| CC | 334 (28.1%) | 87 (24.2%) | 1.000 (reference) | 1.000 (reference) |
| GC | 593 (49.8%) | 187 (52.1%) | 1.211 (0.908–1.614) | 1.237 (0.915–1.672) |
| GG | 263 (22.1%) | 85 (23.7%) | 1.241 (0.883–1.743) | 1.237 (0.866–1.768) |
| rs3741219 | ||||
| AA | 517 (43.5%) | 129 (35.9%) | 1.000 (reference) | 1.000 (reference) |
| GA | 536 (45.0%) | 182 (50.7%) | 1.361 (1.054–1.758) d | 1.429 (1.092–1.817) g |
| GG | 137 (11.5%) | 48 (13.4%) | 1.404 (0.959–2.056) | 1.368 (0.918–2.039) |
a Adjusted for the effects of age and alcohol drinking; b p = 0.012; c p = 0.047; d p = 0.018; e p = 0.020; f p = 0.026; g p = 0.009.