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. 2019 Jul 21;20(14):3565. doi: 10.3390/ijms20143565

Table 2.

Release profile fitting parameters for Weibull, first-order, and Korsmeyer–Peppas equations of ATP and suramin released from different scaffolds. n=3.

Drug Material Model
Weibull First-Order Korsmeyer–Peppas
ATP AG100HA0 R2=0.9962 R2=0.9808 R2=0.9734
Mf=0.923±0.007 Mf=0.90±0.02 K=0.61±0.02 hn
T=0.06±0.06 h B=0.84±0.03 n=0.50±0.07
q=0.83±0.08 h k=1.08±0.08 h−1
AG50HA50 R2=0.9951 R2=0.9143 R2=0.9912
Mf=0.94±0.02 Mf=0.90±0.03 K=0.532±0.003 hn
T=0.00±0.09 h B=0.69±0.06 n=0.24±0.02
q=1.4±0.2 h k=0.48±0.09 h−1
AG33HA67 R2=0.9997 R2=0.9964 R2=0.9959
Mf=0.92±0.02 Mf=0.82±0.02 K=0.064±0.003 hn
T=0.04±0.04 h B=0.80±0.02 n=0.64±0.02
q=34±2 h k=0.040±0.003 h−1
suramin AG100HA0 R2=0.9931 R2=0.9902 R2=0.9989
Mf=1.00±0.02 Mf=0.99±0.02 K=0.706±0.007 hn
T=0.17±0.05 h B=0.99±0.04 n=0.78±0.03
q=0.72±0.07 h k=1.12±0.08 h−1
AG50HA50 R2=0.9941 R2=0.9176 R2=0.9723
Mf=0.90±0.08 Mf=0.76±0.03 K=0.56±0.01 hn
T=0.23±0.02 h B=0.70±0.07 n=0.30±0.04
q=0.9±0.7 h k=1.4±0.3 h−1
AG33HA67 R2=0.9987 R2=0.9396 R2=0.9501
Mf=0.966±0.009 Mf=0.89±0.03 K=0.64±0.06 hn
T=0.060±0.006 h B=0.77±0.05 n=0.465±0.08
q=1.19±0.09 h k=0.9±0.2 h−1