Figure 5.
TRPV4-deficient BMDCs exhibited impaired FcR-dependent phagocytosis. (A) Representative confocal images of wild-type and Trpv4 KO BMDCs after treatment with uncoated or IgG-coated fluorescent microspheres. Scale bar, 20 µm. (B) Percentage of cells with internalized beads. Data were collected from 10 randomly selected fields per condition from three independent experiments. ***, p < 0.001, Fisher’s exact test for the same treatment condition across phenotypes. #, p < 0.001, Fisher’s exact test between different treatment conditions within the same phenotype.