Table 3.
Expression profiles of RAD23B and TYMS proteins and TYMS mRNA.
CR | PR | NR | ||||
---|---|---|---|---|---|---|
Before NCRT |
CISH (TYMS) |
+ | 16.5 | 66.5 | 100 | P = 0.001 |
− | 83.5 | 33.5 | 0 | |||
TYMS (protein) |
+ | 16.5 | 25 | 25 | P = 1.0 | |
− | 83.5 | 75 | 75 | |||
RAD (protein) |
+ | 33.5 | 16.5 | 75 | P = 0.01 | |
− | 66.5 | 83.5 | 25 | |||
After NCRT |
CISH (TYMS) |
+ | 25 | 30 | 100 | P = 0.001 |
− | 75 | 70 | 0 | |||
TYMS (protein) |
+ | 0 | 0 | 83.5 | P = 0.0001 | |
− | 100 | 100 | 16.5 | |||
RAD (protein) |
+ | 0 | 25 | 100 | P = 0.0001 | |
− | 100 | 75 | 0 |
Abbreviations: NCRT: Neoadjuvant chemoradiotherapy; CR: Complete response; PR: Partial response; NR: No response.