Skip to main content
. 2019 Jul 12;11(7):977. doi: 10.3390/cancers11070977

Table 1.

Genes with somatic mutations identified in this study that overlap with TCGA, Chinese, and African American CRC patient data.

Patient Chr Start Stop Reference Alternative Gene Mutation Exonic Function Protein Change Known
p5t 5 112174631 112174631 C T APC SNV Stop gain p.Arg1114Ter rs121913331, COSM13125
p10t 5 112151185 112151185 T G APC SNV Splice Region variant -
p14t 5 112155021 112155022 TG - APC deletion Frame shift variant p.Met431ArgfsTer12
p4low 5 112175639 112175639 C T APC SNV Stop gain p.Arg1450Ter rs121913332, COSM13127
p6low 5 112174249 112174249 T A APC SNV Stop gain p.Tyr986Ter
p7low 5 112174129 112174129 A - APC deletion Frame shift variant p.Cys947ValfsTer8
p7low 5 112175255 112175255 G T APC SNV Stop gain p.Glu1322Ter
p10low 5 112175390 112175391 - A APC Insertion Frame shift variant p.Thr1368AspfsTer7
p11low 5 112175639 112175639 C T APC SNV Stop gain p.Arg1450Ter rs121913332, COSM13127
p12low 5 112155031 112155032 - A APC Insertion Frame shift variant p.Asn436LysfsTer8
p2t 17 7578510 7578510 G - TP53 Deletion Frame shift variant p.C141Afs*29 COSM69019
p10t 17 7576889 7576890 - T TP53 Insertion Frame shift variant p.K320Efs*17
p4t 17 70119862 70119863 - TTCGA SOX9 Insertion Missense mutation p.V291Sfs*94
p5t 17 70119855 70119856 - CGAGA SOX9 Insertion Frame shift variant p.F289Rfs*96
p10t 17 70118889 70118889 A A SOX9 SNV Frame shift variant p.F154Y
p4low 3 41274898 41274898 G C CTNNB1 SNV Missense mutation p.Trp383Ser
p13low 3 41266124 41266124 A G CTNNB1 SNV Missense mutation p.Thr41Ala rs121913412
p14low 3 41266097 41266097 G A CTNNB1 SNV Missense mutation p.Asp32Asn rs28931588
p14low 4 153258983 153258983 G A FBXW7 SNV Stop gain p.Arg278Ter
p14t 4 153268102 153268102 C - FBXW7 Deletion Frame shift variant p.Glu236AsnfsTer3

Chr = Chromosome.