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The localization of tight junction proteins is affected by menstrual cycle. In secretory phase of human endometrium, CLDN-1, -3, -4, and -7 are widely distributed to the lateral region. Tricellulin localized in tricellular contacts of the subapical region, whereas LSR is widely distributed to the lateral region. In proliferative phase, CLDNs localized in the subapical tight junction region. Tricellulin and LSR localized in the subapical tricellular contacts.
