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. 2019 Jul 20;20(14):3555. doi: 10.3390/ijms20143555

Figure 2.

Figure 2

Expression and localization of LSR and tricellulin during endometriosis and in endometrial cancers. LSR and tricellulin localized in tricellular contacts in endometrium. During endometriosis, tricellulin is localized in the subapical region of tricellular contacts and LSR is localized in not only the subapical tricellular contacts but also in the lateral tricellular contacts. In endometrial cancer G1, tricellulin and LSR were distributed unevenly from the subapical to the lateral region of bicellular junctions. In endometrial cancer G2 and G3, the expression levels of tricellulin and LSR were downregulated, resulting in decrease of epithelial barrier and increase of cell migration, cell invasion, and cell growth.