Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Aug 2;5:27. doi: 10.1186/s40851-019-0143-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 8 — Evolutionary scenario of the vertebrate head organizer. Assuming the amphioxus-like chordate ancestor, the vertebrate ancestor should have adopted Wnt signaling for organizer formation and coopted gsc as a target of Lim1 and Otx2 to form the anteriorly enlarged brain by converting the anterior presumptive notochordal cells to the prechordal plate. Schematics of body plans are shown with anterior to the left and dorsal to the top. Orange, brain and neural tube; green, notochord; blue, prechordal plate