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. 2019 Aug 2;14:32. doi: 10.1186/s13024-019-0333-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Granulovacuolar Degeneration and Hirano Bodies. Granulovacuolar degeneration is commonly observed in the neurons of AD (a). As indicated by the arrows, these neurons contain numerous vacuoles housing a dense granule. Additionally, Hirano bodies are often observed as eosinophilic pink rods within the neurons, as shown with the arrowheads (b). The scale bars are 40 μm