Table 2.
Univariate random-effects models for abdominal pain severity (β1) with age as predictor (β2) and with covariates (β3) individually entered
| Mean Values | Standard Deviations | Number | ||||||
|---|---|---|---|---|---|---|---|---|
| (p - values) | ||||||||
| Intercept | Slope | Covariate | ntercept | Slope | Residual Error | |||
| Predictor | β1a | β2a | β3a | σ1b | σ2b | σ3b | Women | Observations |
| Age (47.6 years) | 0.23 | −.003 (0.220) | – | 0.29 | 0.02 | 0.36 | 291 | 6977 |
| Reproductive Aging Markers | ||||||||
| Late Reproductive c | 0.24 (< 0.001) | −0.001 (0.750) | 0.29 | 0.02 | 0.36 | 291 | 6977 | |
| Early MT | − 0.001 (0.970) | |||||||
| Late MT | −0.007 (0.780) | |||||||
| Early PM | − 0.04 (0.160) | |||||||
| Urinary Estrone (ng/mg creatinine, Log10) | 0.20 (< 0.001) | − 0.01 (< 0.001) | − 0.04 (0.020) | 0.28 | 0.01 | 0.35 | 131 | 4908 |
| Urinary FSH (mIU/mg creatintine, Log10) | 0.20 (< 0.001) | −0.01 (< 0.001) | − 0.004 (0.720) | 0.28 | 0.02 | 0.35 | 131 | 4996 |
| Urinary Testosterone (ng/mg creatinine, Log10) | 0.20 (< 0.001) | −0.01 (< 0.001) | − 0.03 (0.020) | 0.28 | 0.02 | 0.35 | 131 | 4975 |
| Stress-related Biomarkers | ||||||||
| Urinary Cortisol (ng/mg creatinine, Log10) | 0.20 (< 0.001) | −0.01 (< 0.001) | − 0.01 (0.310) | 0.28 | 0.02 | 0.35 | 131 | 4993 |
| Urinary Epinephrine (ng/mg creatinine, Log10) | 0.20 (< 0.001) | −0.01 (< 0.001) | 0.0004 (0.940) | 0.28 | 0.01 | 0.35 | 130 | 3325 |
| Urinary Norepinephrine (ng/mg creatinine, Log10) | 0.20 (< 0.001) | −0.01 (< 0.001) | 0.005 (0.820) | 0.27 | 0.01 | 0.35 | 130 | 3329 |
| Stress-related Perceptions | ||||||||
| Perceived Stress (1–6) | 0.21 (< 0.001) | − 0.003 (0.280) | 0.009 (0.060) | 0.29 | 0.02 | 0.36 | 291 | 6977 |
| Tension (0–4) | 0.20 (< 0.001) | −0.003 (0.190) | 0.05 (< 0.001) | 0.28 | 0.02 | 0.36 | 291 | 6977 |
| Anxiety (0–4) | 0.19 (< 0.001) | −0.003 (0.190) | 0.06 (< 0.001) | 0.27 | 0.02 | 0.36 | 291 | 6977 |
a β1, β2, β3 are the fixed effects (group averages) for the intercept, slope and covariate, respectively. β1 represents the mean value in abdominal pain severity for all women in the sample at the mean centered age (47.6 years); β2 represents the rate and direction (+ or -) of change in abdominal pain severity per year; and β3 represents the change in mean abdominal pain severity score for every unit of change in covariate score, when the covariate is added to the model
b σ1, σ2, σ3 are the random effects (variability) for the intercept, slope and residual error, respectively
c Reference group for this categorical variable