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. 2019 Jul 20;8(7):756. doi: 10.3390/cells8070756

Figure 2.

Figure 2

Frequency of mDCs and pDCs in human lymphoid tissue versus peripheral blood. Paired analysis was performed to determine the distribution of mDCs (upper panel, A, B and C) and pDCs (lower panel, D, E and F) in PBMC and LNs of HCs (A and D), RA-risk (B and E) and RA (C and F) individuals. HC (n = 7), RA-risk (n = 21) and RA (n = 8). DCs in PBMC were defined as Lineage-HLA-DR+CD1c+ or CD304+, while DCs in LN tissue were defined as CD45+HLA-DR+CD1c+ or CD304+. For statistical analysis, paired data were analyzed with a Wilcoxon matched pairs test (* p < 0.05 or ** p < 0.01, *** p < 0.001).