Box 2. Diagnostic Criteria for PCOS in Adolescents.

Diagnostic Criteria
Amsterdam criteria (2012) a
Oligoovulation or anovulation
Clinical and/or biochemical signs of hyperandrogenism
Polycystic ovaries on ultrasound
Endocrine Society criteria (2013) b
Oligomenorrhea
Clinical hyperandrogenism and/or hyperandrogenemia
Pediatric Endocrine Society criteria (2015)
Abnormal uterine bleeding pattern
a. Abnormal for age or gynecologic age
b. Persistent symptoms for 1 - 2 years
Evidence of hyperandrogenism
a. Persistent testosterone elevation
b. Moderate-severe hirsutism is clinical evidence of hyperandrogenism
c. Moderate-severe hirsutism or moderate-severe inflammatory acne vulgaris

^aRequired all three Rotterdam criteria to make a diagnosis of PCOS in adolescents.

^bRequired both NIH criteria to make a diagnosis of PCOS in adolescents.