Box 3. Common Laboratory Tests for Adolescents with PCOS Manifestations.

Tests
Hormonal parameters
FSH, LH, estradiol (in particular in adolescents with amenorrhea)
Total or free testosterone
SHBG
DHEAS
17-OH progesterone
TSH
Prolactin
Metabolic parameters
FBS
Fasting insulin
Lipid profiles (TG, TC, LDL-C, HDL-C)

Abbreviations: DHEAS, dehydroepiandrosterone sulfate; FBS, fasting blood sugar; FSH, follicle-stimulating hormone; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; LH, luteinizing hormone; PCOS, polycystic ovary syndrome; SHBG, sex hormone binding globulin; TC, total cholesterol; TG, triglyceride; TSH, Thyroid-stimulating Hormone.