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. 2019 Jul 30;15:2171–2180. doi: 10.2147/NDT.S200045

Table 2.

Outcome at baseline, postintervention, and 1 month follow-up

Measures Groups CE (n=43) or SC (n=48) Baseline mean (SD) Postintervention mean (SD) Follow-up mean (SD) Postintervention Follow-up
P-value (group) P-value (time) Effect size (95% CI) P-value (group) P-value (time) Effect size (95% CI)
MMSE CE 18.72 (4.85) 20.47 (5.75) 19.77 (5.57) 0.344 0.001a d=−1.74 (−2.68,-0.81) 0.247 0.017a d=−1.05 (−1.90,-0.20)
SC 18.40 (5.13) 19.29 (6.00) 18.35 (5.96) 0.066 d=−0.90 (−1.86,0.06) 0.943 d=−0.04 (−1.13,-1.21)
QOL-AD CE 29.14 (5.63) 32.33 (6.47) 31.33 (5.48) 0.110 0.001a d=−3.186 (−4.99, −1.38) 0.030a 0.010a d=2.19 (−3.81, −0.56)
SC 30.98 (5.16) 30.13 (5.96) 28.65 (6.25) 0.181 d=0.854 (−0.41, 2.12) 0.004a d=0.854 (−0.79, 3.87)
CSDD CE 3.79 (2.57) 2.26 (2.49) 2.86 (2.22) 0.060 0.001a d=1.535 (0.70, 2.37) 0.047a 0.012a d=0.930 (0.22, 1.64)
SC 5.04 (4.03) 3.44 (3.26) 4.90 (6.24) 0.015a d=1.60 (0.33, 2.88) 0.872 d=0.146 (−1.67, 1.96)
FACS
Social Communication CE 5.88 (0.96) 6.38 (0.77) 6.41 (0.77) 0.010a 0.003a d=−0.50 (−0.82, −0.18) 0.001a <0.001a d=−0.53 (−0.75, −0.31)
SC 5.83 (0.85) 5.94 (0.81) 5.86 (0.69) 0.151 d=−0.11 (−0.27, 0.04) 0.810 d=−0.03 (−0.27, 0.21)
Communication of Basic Needs CE 5.82 (1.10) 6.35 (0.79) 6.17 (1.06) 0.150 0.003a d=−0.53 (−0.86, −0.20) 0.240 0.069 d=−0.36 (−0.74, 0.03)
SC 6.23 (1.05) 6.56 (0.62) 6.42 (0.86) 0.036a d=−0.34 (−0.65, −0.02) 0.259 d=−0.19 (−0.52, 0.14)

Notes: Effect size was defined as Cohen’s d of the CE group compared with the CG. Mean= adjusted mean after Bonferroni correction. aP<0.05.

Abbreviations: MMSE, Mini-Mental State Examination; QOL-AD, Quality of Life–Alzheimer’s Disease; CSDD, Cornell Scale for Depression in Dementia; FACS, Functional Assessment of Communication Skills; CE, creative expression; SC, standard cognitive; CI, confidence interval.