Table 2.
Baseline Characteristics of Patients with Cancer and Acute Ischemic Stroke Hospitalizations, Stratified by Use of Acute Recanalization Therapies, 1998–2015
| Patient Characteristics*† | Endovascular Therapy (n=2,206) |
Intravenous Thrombolysis (n=10,315) |
No Recanalization Therapy (n=491,856) |
|---|---|---|---|
| Age, mean (SE) | 68.3 (0.7) | 72.1 (0.3) | 72.8 (0.1) |
| Female sex | 1,136 (51.5) | 5,019 (48.7) | 234,632 (47.7) |
| Race/Ethnicity | |||
| White | 1,454 (75.8) | 7,065 (77.1) | 316,022 (77.1) |
| Black | 158 (8.3) | 1,138 (12.4) | 53,730 (13.1) |
| Hispanic | 145 (7.6) | 491 (5.4) | 21,574 (5.3) |
| Asian | 75 (3.9) | 244 (2.7) | 9,064 (2.2) |
| Native American | 0 (0) | 18 (0.2) | 1,271 (0.3) |
| Other | 85 (4.4) | 202 (2.2) | 8,449 (2.1) |
| Stroke risk factors | |||
| Hypertension | 1,116 (50.6) | 5,240 (50.8) | 218,254 (44.4) |
| Atrial fibrillation | 757 (34.3) | 3,313 (32.1) | 103,945 (21.1) |
| Tobacco use | 623 (28.2) | 2,731 (26.5) | 95,040 (19.3) |
| Diabetes mellitus | 516 (23.4) | 2,557 (24.8) | 113,135 (23.0) |
| COPD | 498 (22.6) | 1,994 (19.3) | 104,104 (21.2) |
| Coronary artery disease | 464 (21) | 2,386 (23.1) | 101,048 (20.5) |
| Congestive heart failure | 350 (15.9) | 1,732 (16.8) | 75,098 (15.3) |
| Acute myocardial infarction | 313 (14.2) | 1,107 (10.7) | 50,616 (10.3) |
| Peripheral vascular disease | 246 (11.2) | 891 (8.6) | 35,355 (7.2) |
| Renal disease | 218 (9.9) | 1,344 (13) | 47,271 (9.6) |
| Liver disease | 25 (1.1) | 215 (2.1) | 12,338 (2.5) |
| Charlson comorbidity score, mean (SE) | 3.9 (0.06) | 3.6 (0.03) | 3.4 (0.01) |
| Cancer type‡ | |||
| Non-metastatic solid tumors | 995 (45.1) | 4,783 (46.4) | 198,318 (40.3) |
| Non-metastatic hematologic tumors | 576 (26.1) | 3,271 (31.7) | 123,481 (25.1) |
| Metastatic solid/hematologic tumors | 681 (30.9) | 2,391 (23.2) | 173,921 (35.4) |
Abbreviations: SE, standard error; COPD, chronic obstructive pulmonary disease.
All values are presented as No. (%) unless otherwise specified. Percentages may not add up to 100 because of rounding.
Some patients were treated with both endovascular therapy and intravenous thrombolysis. Endovascular therapy data is only provided from 2006 onward because that is when its procedure code first became available.
Numbers add up to more than the total denominator and percentages add up to more than 100 because some patients had both non-metastatic solid tumors and non-metastatic hematologic tumors. Patients who had diagnosis codes for metastatic and non-metastatic tumors were assigned to the metastatic group.