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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Pharmacol Res. 2019 Jun 6;146:104293. doi: 10.1016/j.phrs.2019.104293

Figure 2: Differentiation of a naïve CD4+ T-lymphocyte.

Figure 2:

Naïve CD4+ T-lymphocytes have several different possible differentiation fates that occur upon activation. Classically, cytokines drive this differentiation, however, neurotransmitters also have complex effects affecting these different polarization states.