Table 2.
Top 10 metabolic pathways of potential biomarkers.
| Pathway name | Total | Hits | p | Log(p) | Holm p | FDR | Impact |
|---|---|---|---|---|---|---|---|
| Arachidonic acid metabolism | 36 | 3 | 0.0069239 | 4.9728 | 0.56084 | 0.40424 | 0.36753 |
| Tryptophan metabolism | 41 | 3 | 0.0099812 | 4.6071 | 0.79849 | 0.40424 | 0.10622 |
| Glutathione metabolism | 26 | 2 | 0.033842 | 3.3861 | 1 | 0.72468 | 0.36642 |
| Steroid hormone biosynthesis | 70 | 3 | 0.041817 | 3.1745 | 1 | 0.72468 | 0.07078 |
| Cyanoamino acid metabolism | 6 | 1 | 0.066665 | 2.7081 | 1 | 0.72468 | 0 |
| Biosynthesis of unsaturated fatty acids | 42 | 2 | 0.080649 | 2.5176 | 1 | 0.72468 | 0 |
| Taurine and hypotaurine metabolism | 8 | 1 | 0.087945 | 2.431 | 1 | 0.72468 | 0 |
| Primary bile acid biosynthesis | 46 | 2 | 0.094426 | 2.3599 | 1 | 0.72468 | 0.05952 |
| Methane metabolism | 9 | 1 | 0.098413 | 2.3186 | 1 | 0.72468 | 0 |
| Vitamin B6 metabolism | 9 | 1 | 0.098413 | 2.3186 | 1 | 0.72468 | 0 |
Note. Total: the number of all metabolites in this pathway; Hits: The number of differential metabolites hitting this pathway; Raw p: P value obtained by enrichment analysis; Holm P: P value corrected by Holm-Bonferroni method; Impact: Impact factor from topological analysis.