TABLE I.

Baseline Characteristics and Plasma Oxytocin Levels in Prader–Willi Syndrome and Healthy Unrelated Control Subjects

	Prader-Willi syndrome (N = 23)	Control subjects (N = 18)
Characteristic	[mean±SD (range)]	[mean ± SD (range)]	F-value	P-value
Age	8.2 ± 2.0 year (5–11 year)	8.2 ± 2.3 year (5–11 year)	0.07	0.79
BMI	20.7 ± 5.0 (l4–28)	18.2 ± 3.3 (15–25)	2.2	0.15
BMI z-score	0.96 ± 1.4 (13–32)	0.52 ± 1.35 (12–26)	1.1	0.31
Percent body fat	33 ± 13% (13–54%)	24 ± 10% (10–47%)	5.5	0.02*
Oxytocin levels [mean pg/ml ± SD (range, N)]
All subjects	167 ± 121 (4.68–391, N = 23)	64.8 ± 83.8 (4.68–247, N = 18)	8.8	0.01*
Female subjects (N = 18)	155 ± 141 (4.68–391, N = 10)	65.3 ± 84.4 (4.68–247, N = 8)	1.4	0.26
Male subjects (N = 23)	172 ± 109 (4.68–332, N = 13)	64.3 ± 87.9 (4.68–245, N = 10)	9.3	0.01*

^*Indicated statistical significance.