Skip to main content
. Author manuscript; available in PMC: 2019 Aug 4.
Published in final edited form as: ACS Nano. 2019 Jan 24;13(2):2083–2093. doi: 10.1021/acsnano.8b08671

Figure 3.

Figure 3.

3D characterization of 6HB DNA-NPs using cryo-EM reconstructions compared with predicted atomic models. (a) The FV tetrahedron of 84-bp edge length shows straight edges with a distinctive FV type and a 3° left-handed twist visible at each vertex, with a clear signature of a 6HB along the edge (arrow). (b) The FV octahedron of 84-bp edge length has straight edges and regular programmed vertices with characteristic open vertices and no detectable deviation along the edge compared to the atomic model, with a clear signature of a 6HB along the edge (arrow). (c) The MV tetrahedron of 84-bp edge length shows the characteristic programmed electron-dense vertex (arrow). (d) The MV octahedron of 84-bp edge length has straight edges and electron-dense vertices with approximately a 1 nm deviation along the edge from the predicted atomic model (arrow). Scale bars are 5 nm.