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In vitro inhibitory activities of HCS-4E-BP1 and -eIF4G peptides as determined via PPI cat-ELCCA. (A) Inhibition of the eIF4E—4E-BP1 PPI by 4E-BP1, HCS-4E-BP1, and HCS-4E-BP1 (LMAA) peptides; and (B) eIF4G, HCS-eIF4G, linear sTIP-04, and sTIP-04 peptides. (C) Table of IC50 values presented as 95% confidence intervals.
