Table 5.
T-score differences in anxiety and depression symptoms per unit change in AChE activity between 2008 and 2016, n=223.
| Score difference (95% CI) per SDa change in AChE (2016-2008) |
|||
|---|---|---|---|
| All Children | 11.0-14.37 y | 14.38-17.9y | |
| Depression | |||
| All | −2.11 (−3.99, −0.24)b | −1.92 (−5.20, 1.35) | −2.21 (−4.68, 0.27) |
| Girls | −3.25 (−6.18, −0.32)b | −4.74 (−9.98, 0.49) | −2.65 (−6.57, 1.27) |
| Boys | −1.13 (−3.68, 1.42) | 0.27 (−4.35, 4.86) | −1.53 (−5.01, 1.94) |
| Anxiety | |||
| All | −0.74 (−2.66, 1.18) | −1.84 (−5.29, 1.60) | −0.15 (−2.61, 2.32) |
| Separation Anxiety | −0.09 (−2.28, 2.10) | −0.71 (−4.20, 2.78) | −0.20 (−3.20, 2.81) |
| GAD Index | −0.91 (−2.87, 1.04) | −3.21 (−6.58, 0.16) | −0.28 (−2.79, 2.24) |
| Social Anxiety | 0.09 (−1.85, 2.03) | −0.83 (−4.39, 2.73) | 0.17 (−2.18, 2.52) |
| Obsessive Compulsive | −1.06 (−3.02, 0.90) | −1.23 (−4.47, 2.01) | −0.72 (−3.40, 1.95) |
a
SD of AChE (2016): 0.55 U/mL
b
p<0.05
GAD: Generalized anxiety disorder
Adjustments: age, gender, AChE activity (2008), hemoglobin concentration (2008 and 2016), and 2016 values for z-scores for height-for-age and BMI-for-age, race, parental years of education and family income. Models stratified by median age categories were not adjusted for age.