Fig. 3.

(A) Post-papillectomy image showing a well-demarcated, elevated firm lesion measuring 1.7×1.5×0.3 cm in size. (B) Histological section (hematoxylin and eosin [H&E], ×40) showing dysplastic glandular cells clustered on the duodenal papillary surface. (C) Non-neoplastic mucosa adjacent to the tumor shows a mixture of irregularly oriented smooth muscle bundles and non-neoplastic biliary glands, suggestive of duodenal papillary involvement (H&E, ×40). (D) Dysplastic glandular cells show enlarged, elongated hyperchromatic nuclei of uniform size, with no loss of polarity, comparable to low-grade dysplasia (H&E, ×400).