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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Exp Mol Pathol. 2019 May 11;109:42–50. doi: 10.1016/j.yexmp.2019.104261

FIG.1. Effect of HNG on Temozolomide (TMZ)-induced weight changes of body, spleen, and liver.

FIG.1.

Mice were treated with vehicle (Control), HNG, TMZ, TMZ+HNG as described in experimental procedures (n=4 in control, 5 each group in the rest). (A) HNG had no significant effect while TMZ significantly decreased body weights when compared to control. HNG significantly prevented TMZ-induced body weights loss (P<0.05). (B) HNG alone increased spleen weights compared with control SCID mice. TMZ significantly decreased spleen weight which were prevented by combined HNG administration (P<0.05). (C) HNG alone did not change liver weight while TMZ significantly decreased liver weight. HNG partially prevented TMZ-suppressed liver weights (P<0.05). Values are means ± SEM.