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. Author manuscript; available in PMC: 2020 Jun 21.
Published in final edited form as: Science. 2019 Jun 21;364(6446):1170–1174. doi: 10.1126/science.aav7019

Fig. 3. Examples of PET tracers synthesized via arene C–H radiofluorination.

Fig. 3.

(A) Maximum intensity projection (MIP) PET images of [18F]-fenoprofen (42) demonstrate higher uptake in TPA-treated mouse ear (A-1) compared with control (A-2) mouse ear. (B) PET/CT images demonstrate preferential tumor (MCF-7) accumulation of 39, compared with longer blood circulation and higher nonspecific binding of 41 at 1 hour after injection. (C) Structures of the tracers used in the preceding panels are shown.