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. 2019 Aug 5;10(8):584. doi: 10.1038/s41419-019-1821-9

Fig. 6. High c-Jun expression levels and loss of PTEN are linked to poor prognosis in melanoma patients.

Fig. 6

a mRNA expression (RNA-Seq) of c-Jun and PI3K/AKT-signaling members show a significant correlation in skin cutaneous melanoma patients (TCGA, Project ID: TCGA-SKCM). Spearman’s correlation is shown for each comparison. The scatter plots show the log2(x + 1) transformed RSEM normalized read counts of each melanoma patient (****P < 0.0001; ***P < 0.001; **P < 0.01; *P < 0.5). b, c Survival rates of the 471 skin cutaneous melanoma patients (TCGA, Project ID: TCGA-SKCM) depicted by PTEN and/or c-Jun expression. Comparison of the survival curves is illustrated in tables (**P < 0.001, Log-rank (Mantel–Cox) test)