Table 2.
DMRs associated with a history of depression
| DMR | Probe ID | Mean Δβ | P-value | Interaction P-value |
|---|---|---|---|---|
| LTB4R2 | ||||
| cg12853742 | −0.04194 | 0.0001 | 0.0195 | |
| cg25576711 | −0.06655 | 0.0004 | 0.0235 | |
| cg26310551 | −0.10142 | 0.0004 | 0.0349 | |
| cg06823034 | −0.08362 | 0.0006 | 0.0433 | |
| cg20007021 | −0.11113 | 0.0006 | 0.0400 | |
| cg21886367 | −0.04719 | 0.0009 | 0.0127 | |
| cg06796435 | −0.07357 | 0.0009 | 0.0311 | |
| cg15364618 | −0.07088 | 0.0010 | 0.0572 | |
| cg10193721 | −0.07892 | 0.0011 | 0.0402 | |
| HOXC4 | ||||
| cg15244786 | 0.08099 | 0.0000 | 0.1128 | |
| cg22370252 | 0.06029 | 0.0001 | 0.1007 | |
| cg26201952 | 0.04552 | 0.0002 | 0.0235 | |
| cg27138204 | 0.04620 | 0.0005 | 0.0855 | |
| cg05992786 | 0.04530 | 0.0032 | 0.6545 | |
| TRIM39 | ||||
| cg04425551 | 0.01938 | 0.0015 | 0.3644 | |
| cg07905808 | 0.01936 | 0.0029 | 0.3694 | |
| cg13079571 | 0.02125 | 0.0054 | 0.4970 | |
| cg11327408 | 0.01720 | 0.0063 | 0.6202 | |
| cg17080697 | 0.01588 | 0.0137 | 0.9874 | |
| cg09020199 | 0.01379 | 0.0435 | 0.9476 | |
| DNAJC17 | ||||
| cg17113968 | 0.02027 | 0.0004 | 0.1187 | |
| cg22079077 | 0.01806 | 0.0004 | 0.2361 | |
| cg16764778 | 0.01619 | 0.0024 | 0.3670 | |
| PNPLA2 | ||||
| cg24427660 | 0.01786 | 0.0014 | 0.2711 | |
| cg18313182 | 0.01371 | 0.0015 | 0.0779 | |
| cg22016649 | 0.01186 | 0.0022 | 0.4433 | |
| cg14522803 | 0.01210 | 0.0188 | 0.2174 | |
| cg06196145 | 0.01298 | 0.0253 | 0.0557 | |
| MEF2A | ||||
| cg01229787 | 0.04985 | 0.0001 | 0.0375 | |
| cg16214653 | 0.02818 | 0.0012 | 0.0296 | |
| cg25885684 | 0.04698 | 0.0023 | 0.0602 |
DMR, differentially methylated region, Mean Δβ; difference between individuals with a history of depression compared to those without, Interaction P-value; P-value of interaction between a history of depression and a history of inflammation, Hg19; Human Genome version 19, GREAT, Genomic Regions Enrichment of Annotations Tool, TSS, transcription start site.