Figure 2.
EP3 receptor expression in SK-BR-3 cells after stimulation. Mean relative EP3 protein expression (n=3)+SEM in SK-BR-3 cells after stimulation with 10, 100 or 1,000 nM of PGE2, sulprostone and L798,106 is shown. Relative expression is normalized to β-actin and to the expression of the control group. *p≤0.05, comparing each stimulation condition to the control group. EP3-antagonism causes a significant reduction of the EP3-expression compared to the control group.