Table 1.
Reagents
| Antibody | Antigen/epitope | Supplier | Host | Reactivity |
|---|---|---|---|---|
| 10G4 | Aβ peptide: N-terminal residues 5 to 17 | Kind gift of Greg Cole (Veterans Affairs Medical Center; University of California)30 | Mouse | Human, mouse |
| 6E10 | N-terminal residues 1 to 16 of Aβ peptide | BioLegend (San Diego, CA) | Mouse | Human |
| mOC1 | Fibrillar aggregates of amyloid-β | Kind gift of Charles Glabe (University of California)31 | Rabbit | Human |
| mOC16 | Fibrillar aggregates of amyloid-β | Kind gift of Charles Glabe31 | Rabbit | Human |
| mOC23 | Fibrillar aggregates of amyloid-β | Kind gift of Charles Glabe31 | Rabbit | Human |
| mOC98 | Fibrillar aggregates of amyloid-β | Kind gift of Charles Glabe31 | Rabbit | Human |
| Anti–PSD-95 antibody | PSD-95 | Millipore (Temecula, CA) | Mouse | Human |
| Synaptophysin antibody | Synaptophysin | Gene Tex (Irvine, CA) | Rabbit | Human, mouse, rat |
| SNAP-25 antibody (SP12) sc-20038 | SNAP-25 | Santa Cruz Biotechnology (Dallas, TX) | Mouse | Human, mouse |
| Anti-apoE goat pAb (178479) | ApoE | Calbiochem (Cambridge, MA) | Goat | Human, mouse, rat |
| E6D7 | ApoE | Abcam (Cambridge, MA) | Mouse | Human, mouse |
| EP1553Y | LDLR | Abcam | Rabbit | Human, mouse |
| EPR3724 | LRP1 | Abcam | Rabbit | Human, mouse, rat, pig |
| Filipin (dye) | Free cholesterol | Sigma-Aldrich (St. Louis, MO) | NA | NA |
| Nile red (dye) | Cholesterol esters | Sigma-Aldrich | NA | NA |
ApoE, apolipoprotein E; NA, not applicable; mOC, OC monoclonal; pAb, polyclonal antibody; postsynaptic density-95, PSD-95; SNAP-25, synaptosomal nerve-associated protein 25.