Table 4.

Summary of Guideline Development Methods

Activity	Yes	No
Panel assembly included experts from various relevant clinical and nonclinical disciplines	✓
Management of conflict of interest in the guideline development group and establishing transparency	✓
Included a methodologist with appropriate expertise (documented expertise in conducting systematic reviews to identify the evidence base and the development of evidence-based recommendations)	✓
Included an individual who represents the views of patients and society at large	✓
Literature review performed in collaboration with methodologists	✓
Searched multiple electronic databases; reviewed reference lists of retrieved articles	✓
Evidence synthesis applied prespecified inclusion and exclusion criteria	✓
Evaluated included studies for sources of bias	✓
Used GRADE to describe quality of evidence	✓
Generation of recommendations used GRADE to rate the strength of recommendations	✓
External review	✓

Definition of abbreviation: GRADE = Grading of Recommendations, Assessment, Development, and Evaluation.