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. 2016 Nov 27;45(2):222–239. doi: 10.1111/apt.13868
Level of evidence Level of agreement
Patients with recurrent C. difficile infection with at least two previous standard treatments without persistent cure should be considered for FMT HIGH 100%
Both standard or family/same household donors are applicable HIGH 100%
If possible, patients should be included in a national registry NA 100%
Faecal samples from patients before and after the treatment, if possible, as well as a donor sample, should be collected for follow‐up in case of adverse events NA 100%
So far, it is still unclear if antibiotic treatment and/or bowel cleansing before FMT is beneficial or if it could negatively affect the outcome (see also ‘Recommendations on preparation of recipient’) NA 90%
No specific route of administration seems to be preferable regarding efficacy. However, preliminary data suggests that application by lower gastrointestinal tract may be safer (see also ‘Recommendations on routes of administration’) LOW 90%

NA, not applicable.