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(A) Schematic representation of cholesterol-modified hyaluronic acid (HA) nanogel formation. (B) Scheme of modification of HA with cholesterol and drug molecules. Reproduced from [55] with permission. Copyright (2013) American Chemical Society. CHA: Cholesterol modified HA; DCM: Dichloromethane; EDC: 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide; HOBT: Hydroxy-benzotriazole; DMSO: Dimethylsulfoxide; DCC: N,N’-Dicyclohexylcarbodiimide.
