Figure 12.
(A) Schematic representation of the preparation of TH287 and siRNA-loaded hyaluronic acid (HA) assembled mesoporous silica nanoparticles (MSNs). Reproduced with permission [72] Copyright 2018 Elsevier Ltd. (B) Confocal microscopy images of HCT-116 cells without any treatment as a control (first row), with the treatment fluorescein isothiocyanate (FITC) labelled HA-MSNs (second row), MSNs (third row), and free HA (10 mg mL−1) combined with FITC labelled HA-MSNs (last row). Reproduced with permission [64] Copyright 2013 The Royal Society of Chemistry. (C) Responsive release of rhodamine B from MSNs-HA by the addition of HAdase solution after incubation for 3 h. Reproduced from [65] with permission. Copyright 2013 John Wiley & Sons, Inc.