Skip to main content
. 2019 Jul 7;11(7):320. doi: 10.3390/pharmaceutics11070320

Table 2.

Percentage of mass aerosol deposition across compartments with different flow rates using the heated/humidified HFNC system.

Compartment 10 L/min
(n = 8)
30 L/min
(n = 7)
50 L/min
(n = 8)
p-Value
Lung (%) 17.23 ± 6.78 5.71 ± 2.04 * 3.46 ± 1.24 ** <0.001 #
Upper airway (%) 34.48 ± 10.25 42.10 ± 13.92 46.07 ± 8.45 0.213
Stomach (%) 0.37 ± 0.15 1.05 ± 1.12 0.35 ± 0.49 0.116
Nebulizer (%) 13.57 ± 7.42 9.43 ± 6.30 10.30 ± 7.12 0.437
Cannula (%) 8.78 ± 3.63 13.18 ± 3.32 *** 18.40 ± 3.48 ** <0.001
Tubing (%) 21.93 ± 4.90 24.99 ± 9.31 23.41 ± 7.17 0.720
Humidifier (%) 12.21 ± 5.47 16.79 ± 9.68 10.95 ± 1.87 0.201 #
Exp Filter (%) 11.40 ± 3.65 5.68 ± 3.17 * 6.82 ± 4.00 0.014

Data is expressed as percentage (mean ± standard deviation). One-way ANOVA and # Kruskal–Wallis Test. p < 0.05. * 10 L/min × 30 L/min, ** 10 L/min × 50 L/min, *** 30 L/min × 50 L/min.