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Prediction of plasma concentration in log scale after a single oral dose of 5, 10, 25, 50, 125, and 250 mg of CKD519 in a 60 kg human using the (a) predicted PK parameters from simple allometry model and the (b) predicted PK parameters from the BrW-adjusted model (horizontal lines represent the IC50 (22 nM and 37 nM), respectively)
