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. 2019 Jul 18;11(7):351. doi: 10.3390/pharmaceutics11070351

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(a) Effect of N/P ratio on Hsp27 gene silencing, (b) inhibition of cell growth, and (c) caspase-3/7 activity in PC-3 cells three days after TEA-core G₇-mediated delivery of 50 nM Hsp27-targeting siRNA in the presence of 10% serum (hot pink bars in all panels). Data for scrambled siRNA–G₇ complexes (gray bars) are shown for comparison. Values are expressed as % relative to control (non-treated cells, green bars). Adapted from [42], with permission of John Wiley and Sons.