Table A2.

Total and effective enthalpy (ΔH_bind, ΔH_bind,eff), entropy (−TΔS_bind, −TΔS_bind,eff), and free energy of binding (ΔG_bind = ΔH_bind−TΔS_bind, ΔG_bind,eff = ΔH_bind,eff−TΔS_bind,eff) for the two dimeric ssiRNAs with G₅ TEA-core PAMAM dendrimers. All values are in kcal/mol (standard deviation for all data in Table A2 is less that 3%). N_eff is the number of positive dendrimer charges effectively involve in ssiRNA binding. Adapted from [57] with permission of the American Society of Chemistry.

Overhangs	ΔHbind	−TΔSbind	ΔGbind		ΔHbind,eff	−TΔSbind,eff	ΔGbind,eff
(A5/A5)2	−1382.7	407.3	−975.4	96	−1260.3	372.7	−887.6
(A7/T7)2	−1480.4	455.9	−1024.5	107	−1441.2	437.2	−1004.0