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. 2019 Jul 18;11(7):350. doi: 10.3390/pharmaceutics11070350

Table 3.

The following table illustrates the results of the three-level factorial design that has been studied for optimization of hydration conditions; the factors were: The volume of the hydrating medium and the time for hydration, and the response is their effect on the % of the entrapment efficiency.

Std Order Formulas The Volume of Hydrating Medium Time for Hydration %Entrapment Efficiency
1 FM 1 10 mL 5 min 84 ± 0.66
2 FM 2 10 mL 30 min 84 ± 0.75
3 FM 3 10 mL 60 min 82 ± 0.28
4 FM 4 15 mL 5 min 82 ± 0.29
5 FM 5 15 mL 30 min 78 ± 0.66
6 FM 6 15 mL 60 min 74 ± 0.74
7 FM 7 20 mL 5 min 81 ± 0.94
8 FM 8 20 mL 30 min 78 ± 0.61
9 FM 9 20 mL 60 min 73 ± 0.31