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. 2019 Jul 13;24(14):2554. doi: 10.3390/molecules24142554

Table 2.

Of cell growth inhibition of MCF-7 and MDA-MB-231 breast cancer cells after 72 h of co-administration of ZER or ZER-HPβCD with TP5-iRGD peptide.

Co-administration Ratio MCF-7 (% of Inhibition) MDA-MB-231 (% of Inhibition)
Compound (IC50): TP5-iRGD ZER ZER-HPβCD ZER ZER-HPβCD
1:10 X 91.4 ± 3.0 90.4 ± 4.2 58.1 ± 8.8 41.5 ± 20.4
1:20 X 67.6 ± 3.9 85.8 ± 7.0 44.0 ± 8.6 72.8 ± 2.3
1:30 X 72.1 ± 8.6 68.5 ± 13.2 48.3 ± 5.4 79.1 ± 1.8

Data are presented as mean ± SD; ZER: zerumbone, ZER-HPβCD: zerumbone encapsulated in hydroxypropyl-β-cyclodextrin.