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. 2019 Jun 28;9(7):395. doi: 10.3390/ani9070395

Table 2.

Metabolites with significantly different levels in the serum of thermal neutral (TN) or heat stress (HS) finishing pigs.

NO. Metabolites RT Quant Mass VIP p Fold Change
Gut Microbiome-Derived Metabolites
1 fluorene 9.41 204 2.60 0.009 1.51
2 lyxose 1 9.46 103 1.87 0.039 1.62
3 d-galacturonic acid 10.97 333 2.14 <0.001 1.76
Fatty Acid Metabolism
4 3-Hexenedioic acid 8.65 170 1.91 0.049 2.10
5 myristic Acid 10.57 285 1.81 0.026 1.55
6 palmitic acid 11.56 117 1.96 0.043 1.55
7 arachidonic acid 13.02 80 1.16 0.034 0.76
8 3-Aminoisobutyric acid 1 8.29 174 1.36 0.020 1.23
9 3-hydroxybutanoic acid 5.91 131 2.10 0.037 1.87
10 maleic acid 7.18 341 1.70 0.017 1.84
11 tartaric acid 9.31 355 1.91 0.027 1.46
Carbohydrate Metabolism
12 glucose 2 10.90 103 1.58 <0.001 0.52
13 mannose 2 10.82 160 2.23 <0.001 0.65
14 lactose 1 14.21 73 1.58 0.027 0.30
15 3,6-Anhydro-D-galactose 10.00 231 1.45 0.015 0.58
16 6-phosphogluconic acid 13.16 318 2.17 0.006 0.73
17 ribonic acid, gamma-lactone 9.70 68 2.31 0.024 1.53
18 Glucoheptonic acid 12.61 232 2.14 0.023 1.72
Amino Acid Metabolism
19 lysine 10.95 174 1.39 0.015 1.71
20 N-Methyl-DL-alanine 6.25 130 1.88 0.050 2.19
Amines Metabolism
21 hydroxylamine 5.88 245 1.62 0.031 1.56
22 N-Acetyl-5-hydroxytryptamine 2 13.57 55 1.95 0.049 0.15
23 3-methylcatechol 7.90 180 2.34 0.012 0.53
24 indole-3-acetamide 12.58 105 1.76 0.016 0.52

RT, retention time; VIP, variable importance in the projection; Fold Change, ratio of mean peak area of the HS group to the mean peak area of the TN group.