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. 2019 Jun 29;7(7):189. doi: 10.3390/microorganisms7070189

Table 4.

General characteristics of the included studies.

First Author Study Design (No. of Subjects) Laser Type Laser Parameters Evaluated Bacteria
Birang et al. [30] RCT diode 810 nm, 300 mW, 30 s per site, large-area handpiece (transgingival) or bulb fiber (intra-pocket) or bare fiber (granulation tissues), irradiation repeated after 2 weeks Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Treponema denticola, Tannerella forsythia
Caccianiga et al. [31] prospective case series diode (aPDT) 2.5 W, 0.5 W (mean power), 10 kHz, T-on 20 us, T-off 80 us, 60 s per site, 400 micron fiber, periodontal and peri-implant pocket site, irradiation repeated after 15 days and then for the next 3 months every 20 days,
3% hydrogen peroxide
Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, Fusobacterium nucleatum, Campylobacter rectus, Eikenella corrodens
Persson et al. [32] RCT Er:YAG 100 mJ/pulse, 10 Hz (12.7 J/cm), cone-shaped sapphire tip, parallel mode, pocket site 74 specimens (Campylobacter showae, Capnocytophaga ochracea, P. melaninogenica, S. anaerobius, S. hae- molyticus, S.intermedius, and S. mutans)
Arisan et al. [33] RCT diode 810 nm (energy density, 3 J/cm2; power density, 400 mW/cm2; energy 1.5 J; spot diameter, 1 mm), 60 s per site, pulsed mode, power level of 1 W, 400 um optical fiber tip, peri-implant pocket area 20 specimen (Tannerella forsythia, Treponema denticola, Porphyromonas gingivalis, Campylobacter rectus, Prevotella intermedia, Peptostreptococcus micros, Fusobacterium nucleatum, Eubacterium nodatum, Streptococcus constellatus group, Campylobacter gracilis, Prevotella nigrescens)
Yoshino et al. [34] prospective case series Er:YAG 150 mJ (10 ps), 40 mJ (10 pps), 70 mJ (25 pps), straight tip (bone area), side tip (implant area), straight-and-side (gingival sulcus area) Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Treponema denticola, Tannerella forsythia
Bassetti et al. [14] RCT diode (aPDT) 660 nm, 100 mW, 10 s per site, peri-implant pocket area, irradiation repeated after 1 week
toluidine blue O dye (TBO)
Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Treponema denticola, Tannerella forsythia, Fusobacterium nucleatum, Campylobacter rectus, Capnocytophaga gingivalis, Parvimonas micra, Eubacterium nodatum, Eikenella corrodens
Dörtbudak et al. [76] prospective case series diode (aPDT) 690 nm, 60 s per site, implant and per-implant pocket site
TBO
Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia