Table 5.

Follow-up and microbial test assessment of the included studies.

First author	Subject Groups	Microbial Genome Evaluation	Follow-Up
Birang et al. [30]	Control (mechanical debridement + diode laser), test (mechanical debridement + diode laser EmunDo)	real-time polymerase chain reaction (RT-PCR) technique	3 months
Caccianiga et al. [31]	Only one group (aPDT Oxylaser)	real-time polymerase chain reaction (RT-PCR) technique	6 months
Persson et al. [32]	Test 1 (Er:YAG laser), test 2 (air-abrasive device)	DNA–DNA hybridization method	6 months
Arisan et al. [33]	Control (mechanical debridement), test (mechanical debridement + diode laser)	polymerase chain reaction (PCR) technique	6 months
Yoshino et al. [34]	Only one group (Er:YAG laser)	polymerase chain reaction (PCR) technique	2 years
Bassetti et al. [14]	Control (mechanical debridement), test (mechanical debridement + aPDT)	real-time polymerase chain reaction (RT-PCR) technique	12 months
Dörtbudak et al. [76]	Control (no treatment), test 1 (dye), test 2 (dye + laser—aPDT)	gram staining, colony morphology, positive catalase reaction, BANA, hydrolytic activity, a-glucosidase activity, ß-galactosidase, esculin hydrolysis and indole test	Right after the therapy