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A novel 3D bioprinting approach with hydrogel bioinks functionalized with luminescent nanoparticles. (a) Cells and/or nanoparticles, containing the O2-sensitive luminescent indicator PtTFPP compound and an inert fluorescent coumarin dye, were incorporated into an alginate-based bioink for bioprinting. (b) Experimental setup used to image O2 distribution in bioprinted hydrogel constructs.
